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Bioavailability VS. Bioactivity



A whole science exists which quantifies the different ways in which drugs interact with our bodies. Pharmacokinetics (PK) quantifies where we can find a drug from the moment it’s ingested, to the moment it is gone. Summarized by the neat acronym ADME (Absorption, Distribution, Metabolism, and Excretion), PK tells us how much of the compound reaches the target tissue. In the case of cannabinoids, this may be the central nervous system, the GI tract, nerve endings, or cutaneous vasculature. These parameters are separate from Bioactivity, determined by the branch called Pharmacodynamics, which tells us how much a targeted receptor or signaling system is influenced in the presence of the drug that’s there.

Table of contents
00:00:20 Introduction
00:04:10 Correlation between water-solubility and bioactivity
00:06:30 Studying CBD safety
00:11:18 Water-soluble CBD and nanoparticles
00:13:44 Brain scanning
00:16:35 Bioavailability vs bioactivity
00:21:26 Bioavailability and bioactivity for entrepreneurs
00:31:08 Q&A

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